Many of the toxicities are functional in nature and/or in origin. Whereas pharmacological responses tend to be fairly rapid in onset, and are therefore detectable after a single dose, some diminish on repeated dosing, whereas others increase in magnitude and therefore can be missed or underestimated in single-dose, safety pharmacology studies.
We have state of the art equipment available at close proximity so that sensitivity of the methods can be detected in small, clinically relevant, changes.

At Aaranya Biosciences careful pharmacological validation of methods are used to establish their detection sensitivity that is vital to ensure the credibility of generated data.

Toxicity testing can be very specific for a particular effect, such as dermal irritation, or it may be general, such as testing for unknown chronic effects.